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경락경혈학회> Korean Journal of Acupuncture

Korean Journal of Acupuncture update

  • : 경락경혈학회
  • : 의약학분야  >  기초한의학
  • : KCI등재
  • :
  • : 연속간행물
  • : 계간
  • : 2287-3368
  • :
  • : 대한경락경혈학회지(~2012)→Korean Journal of Acupuncture(2012~)

수록정보
수록범위 : 17권1호(2000)~36권2호(2019) |수록논문 수 : 808
Korean Journal of Acupuncture
36권2호(2019년 06월) 수록논문
최근 권호 논문
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KCI등재

1내장감각과민의 침구 치료에 대한 실험연구 현황: PubMed를 중심으로

저자 : 한창우 ( Chang Woo Han ) , 최준용 ( Jun-yong Choi ) , 박성하 ( Seong Ha Park ) , 김소연 ( So Yeon Kim )

발행기관 : 경락경혈학회 간행물 : Korean Journal of Acupuncture 36권 2호 발행 연도 : 2019 페이지 : pp. 93-103 (11 pages)

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Objectives : The aim of this study is to review the current trends in experimental studies on the acupuncture moxibustion treatment for visceral hypersensitivity. Methods : PubMed was searched for experimental studies about visceral hypersensitivity and acupuncture/moxibustion. Data were extracted and tabulated from the selected articles about experimental method, intervention, result and mechanism. Results : Total 23 articles were reviewed. Chronic visceral hypersensitivity animal model was applied in 17 studies (74%). Visceral hypersensitivity was measured by abdominal withdrawal reflex scoring or/and abdominal electromyogram. Acupoints like ST25, ST36, ST37, BL25, LI11, BL32 and PC6 were treated by electroacupuncture or moxibustion. All articles reported that electroacupuncture or moxibustion treatment is significantly effective in reducing visceral hypersensitivity. Treatment mechanisms were studied, related to mast cell, serotonin (5-HT) and receptor (5-HT3R and 5-HT4R), substance P (SP), vasoactive intestinal polypeptide (VIP), c-fos positive cell, corticotropin-releasing hormone (CRH), purinergic 2X (P2X)2, P2X3, P2X4, P2X7, N-methyl-D-aspartate (NMDA) receptor (NR1 and NR2B), prokinectin (PK) 1 and PK2. Conclusions : Evidences on acupuncture/moxibustion treatment for visceral hypersensitivity in animal studies warrant more research on effective acupoins, electro-acupuncture methods and treatment durations.

KCI등재

2퇴행성 슬관절염의 화침 치료에 대한 체계적 문헌 고찰 및 메타분석: 최근 5년간의 호침 치료 비교 연구를 중심으로

저자 : 고홍제 ( Hong-je Ko ) , 유재희 ( Jae-hee Yoo ) , 신정철 ( Jeong-cheol Shin )

발행기관 : 경락경혈학회 간행물 : Korean Journal of Acupuncture 36권 2호 발행 연도 : 2019 페이지 : pp. 104-114 (11 pages)

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Objectives : The purpose of this study is to review the effectiveness of fire needling treatment for knee osteoarthritis in comparison with manual acupuncture treatment. Methods : Through four foreign online databases (PubMed, Cochrane library, EMBASE, and CNKI) and five domestic online databases (NDSL, RISS, KISS, OASIS, and KTKP), we searched for clinical studies that performed fire needling treatment for knee osteoarthritis until May 10, 2019. Only randomized controlled trials were selected and we assessed the risk of bias according to the Cochrane RoB criteria. This review examined the selected studies into first author, publication year, sample size, outcome measurements, results, acupoints, treatment time & period and so on. Results : A total of 7 RCTs were selected in this review and all were conducted in China. Treatment period of more than 4 weeks and treatment visits of 10 to 20 times were the most common. EX-LE4 and ST35 (=EX-LE5) acupoints were most frequently selected in treatment. Among the evaluation indexes, a total efficacy rate was used the most. Most of fire needling groups showed more significant results compared with the manual acupuncture groups statistically. Conclusions : All studies showed that fire needling treatments for knee osteoarthritis were more effective than manual acupuncture treatments statistically. Therefore, the results of this study could be utilized as a preliminary data for another clinical research on fire needling treatment for knee osteoarthritis. However, further well-designed randomized controlled trials will be needed to develop sufficient evidence about the effectiveness and safety of fire needling treatment for knee osteoarthritis in the future.

KCI등재

3연교의 파골세포 분화 및 골 흡수 억제 기전 연구

저자 : 엄지환 ( Ji-whan Eom ) , 김재현 ( Jae-hyun Kim ) , 김민선 ( Minsun Kim ) , 김상우 ( Sangwoo Kim ) , 신화정 ( Hwajeong Shin ) , 정혁상 ( Hyuk-sang Jung ) , 손영주 ( Youngjoo Sohn )

발행기관 : 경락경혈학회 간행물 : Korean Journal of Acupuncture 36권 2호 발행 연도 : 2019 페이지 : pp. 115-126 (12 pages)

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Objectives : Osteoporosis is a condition characterized by low bone mass and increased bone fragility. It has become a major problem of senior citizens. The purpose of this study is to experiment the effect of water extract of Forsythiae Fructus (wFF) on osteoclast differentiation; and the other purpose is to examine the effect of wFF on osteoporosis in ovariectomized rat. Methods : To investigate the effect of wFF on osteoclast differentiation and activity, RAW 264.7 cells were used. The number of TRAP positive cell, TRAP activity, pit area, mRNA expression of makers (RANK, TRAP, CA II, CTK, MMP-9, NFATc1, c-Fos), protein expression of makers (NFATc1, c-Fos) were investigated. For in vivo study, 40 female Sprague-Dawley (SD) rats were induced osteoporosis by ovariectomy (OVX) and then tested for anti-osteoporosis effect by administration of wFF. Results : wFF suppressed osteoclatogenesis, TRAP activity and pit area formation. Moreover, wFF decreased the expression of master differentiation factors (NFATc1, c-Fos) and also reduced the osteoclastogenesis-related markers (TRAP, CA II, CTK, MMP-9). These suggest that wFF inhibit osteoclasts differentiation and bone resorption. In the OVX rat model, wFF inhibited decreasing of BMD and trabecular area. Conclusions : Forsythiae Fructus should be effective for osteoporosis prevention and treatment.

KCI등재

4원엽모고채 약침의 설치류에 대한 단회 및 반복 독성연구

저자 : 이용은 ( Yong Eun Lee ) , 이정희 ( Jung Hee Lee ) , 이윤규 ( Yun Kyu Lee ) , 이봉효 ( Bong Hyo Lee ) , 김재수 ( Jae Soo Kim ) , 이현종 ( Hyun-jong Lee )

발행기관 : 경락경혈학회 간행물 : Korean Journal of Acupuncture 36권 2호 발행 연도 : 2019 페이지 : pp. 127-138 (12 pages)

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Objectives : This study was carried out in order to toxicity and safety of Drosera Rotundifolia L. pharmacopuncture in BALB/c mice. Methods : In order to investigate toxicity and safety of Drosera Rotundifolia L. pharmacopuncture, BALB/c mice were chosen in these studies and injected to ST36. In 50% Lethal Dose (LD 50) study, mice were divided into 8 groups. Doses of pharmacopuncture at 300, 600, 1,200, 2,400, 3,600, 4,800, 6,000, 7,200 mg/kg were given to the each group. we observed mortality and toxic signs for 7 days after injection. In single-dose toxicity, mice were divided into 4 groups. Doses of pharmacopuncture, 300, 600, 1,200 mg/kg, were administered to the experimental group. And a dose of normal saline, 0.2 ml was administered to the control group. We observed mortality and toxic signs for 14 days after injection. In repeated-dose toxicity for 4 weeks, mice were divided in 4 groups. Doses of pharmacopuncture, 150, 300, 600 mg/kg, were administered to the experimental group. And a dose of normal saline, 0.2 ml, was administered to the control group. We observed mortality, toxic signs, body weight, hematological values et al. Results : The LD 50 of Drosera Rotundifolia L. pharmacopuncture was 4,800 mg/kg. In single-dose toxicity, no deaths, no toxic signs occurred in any of groups. In repeated-dose toxicity for 4 weeks, no deaths, no toxic signs occurred in any of groups. Conclusions : No Observed Adverse Effect Level (NOAEL) of Drosera Rotundifolia L. pharmacopuncture injection for 4 weeks was more than 600 mg/kg.

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