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대한류마티스학회> Journal of Rheumatic Diseases(구 대한류마티스학회지)

Journal of Rheumatic Diseases(구 대한류마티스학회지) update

  • : 대한류마티스학회
  • : 의약학분야  >  정형외과학
  • : KCI등재
  • :
  • : 연속간행물
  • : 계간
  • : 2093-940X
  • : 2233-4718
  • : 대한류마티스학회지(~2010) → journal of rheumatic diseases(2011~)

수록정보
18권1호(2011) |수록논문 수 : 14
간행물 제목
18권1호(2011년) 수록논문
권호별 수록 논문
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1논평 : 한국에서 흔한 주류의 퓨린 농도

저자 : 이영호 ( Young Ho Lee )

발행기관 : 대한류마티스학회 간행물 : Journal of Rheumatic Diseases(구 대한류마티스학회지) 18권 1호 발행 연도 : 2011 페이지 : pp. 1-2 (2 pages)

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2종설 : 흔히 접하는 어깨질환

저자 : 김양수 ( Yang Soo Kim ) , 옥지훈 ( Ji Hoon Ok )

발행기관 : 대한류마티스학회 간행물 : Journal of Rheumatic Diseases(구 대한류마티스학회지) 18권 1호 발행 연도 : 2011 페이지 : pp. 3-10 (8 pages)

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There are various different conditions that can lead to shoulder pain. The most common cause is rotator cuff disease, including impingement syndrome and rotator cuff tear. For satisfactory treatment outcome, it is important to understand the pathophysiology of rotator cuff disease and the treatment method must be based on these understandings. Frozen shoulder and calcific tendinitis are also common causes of shoulder pain. Because of self-healing abilities of these diseases, the treatment may be passive and neglected. However, without proper management, complications can remain, such as stiffness and pain. Even though various conservative treatments have yielded satisfactory results, surgical treatment should be considered if these have failed.

KCI등재

3원저 : 류마티스관절염 활액 대식세포에서 파골세포 분화 관련 유전자의 발현

저자 : 이영호 ( Young Ho Lee ) , 김태환 ( Tae Hwan Kim ) , 최성재 ( Sung Jae Choi ) , 송관규 ( Gwan Gyu Song ) , 지종대 ( Jong Dae Ji ) , 이빛나라 ( Bit Na Ra Lee )

발행기관 : 대한류마티스학회 간행물 : Journal of Rheumatic Diseases(구 대한류마티스학회지) 18권 1호 발행 연도 : 2011 페이지 : pp. 11-18 (8 pages)

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To examine the mechanism for the inhibited differentiation of osteoclasts in rheumatoid arthritis synovial CD14+ osteoclast precursors, the different expressions of the osteoclastogenesis-related genes in rheumatoid arthritis (RA) synovial fluid CD14+ osteoclast precursors were compared with those of normal peripheral blood (PB) CD14+ osteoclast precursors. Methods. The expression of osteoclastogenesis-related genes were examined using a gene expression oligonucleotide microarray. To validate the results of the microarray analysis, the mRNA expressions of osteoclastogenesis-related genes were measured by real-time PCR. Results. Comparative analysis of the mRNA profiles showed significantly different expression of osteoclastogenesis-related genes, such as MafB, Id3 and LILRB4, in the RA synovial CD14+ osteoclast precursors, compared to that of normal PB CD14+ osteoclast precursors. Conclusion. The expression of the osteoclastogenesis-related genes in RA synovial CD14+ osteoclast precursors is different from that of the normal PB CD14+ osteoclast precursors. These results suggest that the different expression of osteoclastogenesis-related genes might be involved in the altered osteoclastogenesis in RA synovial osteoclast precursors.

KCI등재

4원저 : 한국인 전신홍반루푸스 환자에서 골밀도 감소의 위험인자

저자 : 박윤정 ( Yun Jung Park ) , 박보형 ( Bo Hyoung Park ) , 민도준 ( Do June Min ) , 김완욱 ( Wan Uk Kim )

발행기관 : 대한류마티스학회 간행물 : Journal of Rheumatic Diseases(구 대한류마티스학회지) 18권 1호 발행 연도 : 2011 페이지 : pp. 19-25 (7 pages)

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To determine the degree and risk factors for decreased bone mineral density (BMD) in patients with systemic lupus erythematosus (SLE). Methods. One hundred and one patients with SLE and 57 age-and gender-matched healthy controls were enrolled in this study. The BMD was measured by dual energy X-ray absorptiometry (DXA). The laboratory findings and clinical variables evaluated in the SLE patients consisted of disease duration, SLE disease activity index (SLEDAI), and medications, including mean and cumulative dose of glucocorticoid. At the time of the clinical and laboratory assessment, the levels of serum osteocalcin, serum FSH/ LH, urine deoxypyridinoline (DPD), and serum cytokines, such as IL-6 and soluble receptor activator of NF-kB ligand (RANKL), were determined in SLE patients using a enzyme-linked immunosorbent assay. Results. The BMD T score decreased in patients with SLE compared to the healthy controls (-1.11 versus -0.41, p=0.001 at lumbar spine, -0.84 versus -0.01, p<0.001 at femur neck, -1.20 versus -0.45, p<0.001 at total hip, respectively). Osteoporosis and osteopenia was present in 16.8% and 46.5% of patients, respectively. Multiple regression analysis revealed a low BMD in the lumbar spine to be associated with increased FSH, low BMI and cumulative glucocorticoid dose. A low BMD in the hip and femur neck was associated with increased FSH, low BMI, and duration of glucocorticoid. On the other hand, the levels of osteocalcin, deoxypyridinoline (DPD), IL-6, and soluble RANKL were similar in patients with a low BMD and those with normal BMD. Conclusion. Osteoporosis and osteopenia are more common in young Korean SLE patients than in control subjects. Elevated FSH, low BMI, and the use of glucocorticoid are independent risk factors linked to a decreased BMD in Korean patients with SLE.

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5원저 : 요산저하 치료가 통풍 환자의 신기능에 미치는 영향

저자 : 이찬희 ( Chan Hee Lee ) , 박용범 ( Yong Beom Park ) , 조소영 ( So Young Jo )

발행기관 : 대한류마티스학회 간행물 : Journal of Rheumatic Diseases(구 대한류마티스학회지) 18권 1호 발행 연도 : 2011 페이지 : pp. 26-31 (6 pages)

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Hyperuricemia is known as a risk factor that causes and worsens kidney diseases through a variety of mechanisms. Recent animal studies reported that the correction of hyperuricemia improved the renal function, but there have been few human studies. This study examined whether a hypouricemic treatment affects the renal function in Korean patients with gout. Methods. Two hundred sixty-seven gout patients who were prescribed uric acid lowering agents for more than 1 year were enrolled at the Division of Rheumatology in the National Health Insurance Corporation Ilsan Hospital and Yonsei University Severance Hospital from January 2005 to January 2010. The following were examined: the levels of serum uric acid and serum creatinine, the amount of 24-hour urine uric acid, glomerular filtration rate (GFR), and abdominal ultrasound findings at baseline and follow-up. Results. Mean age of the study subjects was 54.4±13.9 years. Two hundred forty-seven patients were male and 20 patients were female. The mean treatment duration was 35.0±19.5 months. Among the 267 patients, 219 and 19 patients received monotherapy with allopurinol and benzbromarone respectively, and 29 patients received combination therapy with allopurinol and benzbromarone. After the treatment with uric acid lowering agents, the serum uric acid and creatinine levels decreased significantly (8.05±1.96 mg/dL vs 6.16±1.46 mg/dL, p<0.001, 1.25±0.46 mg/dL vs 1.18±0.42 mg/dL, p=0.001, respectively) and the GFR increased significantly (74.4±27.0 mL/min/1.73 m3 vs 80.2±31.6 mL/min/1.73 m3, p<0.001). Conclusion. Treatment with hypouricemic agents reduced the levels of serum uric acid and improved the renal function. These results suggest that a hypouricemic treatment might improve the kidney function in gout patients.

KCI등재

6증례 : 류마티스관절염 양상으로 발현된 췌장암의 부종양성 증후군 1예

저자 : 김태종 ( Tae Jong Kim ) , 김영일 ( Young Il Kim ) , 이호준 ( Ho Jun Lee ) , 이경은 ( Kyung Eun Lee ) , 박용욱 ( Yong wook Park ) , 최선규 ( Seon Gyu Choi ) , 이신석 ( Shin Seok Lee ) , 서성례 ( Seong Rye Seo ) , 이성지 ( Sung Ji Lee )

발행기관 : 대한류마티스학회 간행물 : Journal of Rheumatic Diseases(구 대한류마티스학회지) 18권 1호 발행 연도 : 2011 페이지 : pp. 32-35 (4 pages)

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Paraneoplastic cancer polyarthritis is a very rare manifestation of musculoskeletal disorders associated with several solid and hematologic malignancies. We describe a 71-yearold woman who presented initially with an abrupt onset of rheumatoid arthritis-like symmetrical polyarthritis. The patient was diagnosed with pancreatic cancer with multiple hepatic metastases approximately six months later. Her symptoms of polyarthritis improved after the introduction of medication including non-steroidal anti-inflammatory drugs and disease modifying anti-rheumatic drugs. This case suggests that a hidden malignancy should always be considered in elderly patients, who present with an abrupt onset of symmetric polyarthritis for the first time in their life.

KCI등재

7증례 : 급성 다발성 관절염으로 발병한 카플란 증후군 1예

저자 : 이은봉 ( Eun Bong Lee ) , 김혜원 ( Hye Won Kim ) , 신기철 ( Ki Chul Shin ) , 송영욱 ( Yeong Wook Song ) , 임재준 ( Jae Joon Yim ) , 장성혜 ( Sung Hae Chang ) , 류한희 ( Han Hee Ryu )

발행기관 : 대한류마티스학회 간행물 : Journal of Rheumatic Diseases(구 대한류마티스학회지) 18권 1호 발행 연도 : 2011 페이지 : pp. 36-40 (5 pages)

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Caplan originally described distinctive pulmonary nodules in miners who had suffered from rheumatoid arthritis. Later, the pulmonary nodules, together with a history of rheumatoid arthritis and exposure to inorganic dust were called Caplan`s syndrome. This syndrome has been described by case reports in many countries but only two cases have been reported in Korea up to now. The patient in this case report was a 70-years-old man who had worked in the construction field for 20 years mainly demolishing buildings. He was diagnosed with silicosis by a lung biopsy 1 year prior to admission. He suddenly developed arthralgia and morning stiffness in multiple joints 2 weeks prior to admission. Chest imaging revealed aggravation of the bilateral pulmonary nodules. He was diagnosed with seropositive rheumatoid arthritis. The lung nodules, arthralgia, and morning stiffness improved clinically after treatment with the corticosteroid and disease modifying anti-rheumatic drugs.

KCI등재

8증례 : 종양괴사인자 차단제 사용 후 발생한 사르코이드증 1예

저자 : 김태환 ( Tae Hwan Kim ) , 김은경 ( Eun Kyoung Kim ) , 이강원 ( Kang Won Lee ) , 정경희 ( Kyong Hee Jung ) , 백승삼 ( Seung Sam Paik ) , 박수역 ( Soo Yuck Park ) , 황덕원 ( Deok Won Hwang )

발행기관 : 대한류마티스학회 간행물 : Journal of Rheumatic Diseases(구 대한류마티스학회지) 18권 1호 발행 연도 : 2011 페이지 : pp. 41-45 (5 pages)

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Etanercept is a soluble receptor fusion protein that inhibits tumor necrosis factor-alpha(TNF-α). The receptor is used widely in the treatment of ankylosing spondylitis, rheumatoid arthritis, sarcoidosis and other indications. For sarcoidosis, it potentially suppresses granuloma formation with TNF-α blocking. On the other hand, recent studies have suggested that paradoxical sarcoidosis can be induced by TNF-α antagonists in some cases. A 42-yearold woman, who was treated with etanercept due to ankylosing spondylitis for 5 years, was admitted because of right suprahilar lymphadenopathy on chest radiography. Chest computed tomography revealed an enlargement of supraclavicular, paratracheal, mediastinal lymph nodes. She was diagnosed with sarcoidosis on the supraclavicular lymph node biopsy, which was non-caseating epithelioid cell granuloma and excluded from similar diseases. She was treated for sarcoidosis with prednisolone instead of etanercept.

KCI등재

9증례 : 갑상선 암 진단 중 발견된 이차성 항인지질항체 증후군 1예

저자 : 이영호 ( Young Ho Lee ) , 최성재 ( Sung Jae Choi ) , 송관규 ( Gwan Gyu Song ) , 지종대 ( Jong Dae Ji ) , 강승훈 ( Seung Hun Kang )

발행기관 : 대한류마티스학회 간행물 : Journal of Rheumatic Diseases(구 대한류마티스학회지) 18권 1호 발행 연도 : 2011 페이지 : pp. 46-49 (4 pages)

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Antiphospholipid antibody syndrome (APS) is defined as the presence of lupus anticoagulant antibody or anticardiolipin antibody with vascular thrombosis or pregnancy complications. APS can be associated with autoimmune disease or infectious disease. APS has also been reported in conjunction with variety of solid and hematologic malignancies. There were some reports on APS which were accompanied by hematologic malignancy, but there was no report with solid malignancy in Korea. We experienced one case of secondary APS, which was diagnosed during pre-operative evaluation of thyroid cancer. This patient had prolonged aPTT (activate partial thromboplastin time) and decreased coagulation factors which were regarded as hemophilia at first. Although the precise mechanism of the relationship between APS and cancer has not been proven thoroughly, APS can be accompanied by various malignancies. So proper screening and early detection of malignancies in APS patients are recommended.

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10증례 : 레이노 현상에 의한 수지 괴사로 진단된 원발쓸개관간경화 1예

저자 : 이우제 ( Woo Je Lee ) , 강종식 ( Jong Sik Kang ) , 이기업 ( Ki Up Lee ) , 박중열 ( Joong Yeol Park ) , 이상아 ( Sang Ah Lee ) , 황윤우 ( Yoo Noo Hwang ) , 윤환 ( Hwang Yoon )

발행기관 : 대한류마티스학회 간행물 : Journal of Rheumatic Diseases(구 대한류마티스학회지) 18권 1호 발행 연도 : 2011 페이지 : pp. 50-54 (5 pages)

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Necrosis of the upper extremity occurs rarely in type 2 diabetic patients compared to lower extremity necrosis. We report a 69-year-old woman with type 2 diabetes mellitus who presented with necrosis of the left 5th finger tip. The patient had primary biliary cirrhosis accompanied by necrosis of the fingertip due to severe Raynaud`s phenomenon. Primary biliary cirrhosis (PBC) is a typical autoimmune disease, which can in rare cases be accompanied by autoimmune symptoms including sicca symptom and Raynaud`s phenomenon. Furthermore, autoimmune diseases, such as systemic sclerosis, rheumatoid arthritis and undifferentiated connective tissue disease (UCTD) can be associated. Although every type of vascular etiology should be considered as a cause of digital necrosis, Raynaud`s phenomenon is usually not considered in diabetes. We report this case of finger tip necrosis due to severe Raynaud`s phenomenon accompanied by PBC and UCTD in a diabetic patient.

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